Index
of 2009 Publications
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Samlowski WE, Moon J, Tuthill RJ, Heinrich MC, Balzer-Haas NS, Merl SA, Deconti RC, Thompson JA, Witter MT, Flaherty LE, Sondak VK.
A Phase II Trial of Imatinib Mesylate in Merkel Cell Carcinoma (Neuroendocrine Carcinoma of the Skin):
A Southwest Oncology Group Study (S0331).
Am J Clin Oncol. 2009 Dec 16. [Epub ahead of print]
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PMID: 20019577
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Sadow PM, Heinrich MC, Corless CL, Fletcher JA, Nosé V.
Absence of BRAF, NRAS, KRAS, HRAS Mutations, and RET/
PTC Gene Rearrangements Distinguishes Dominant Nodules
in Hashimoto Thyroiditis from Papillary Thyroid
Carcinomas.
Endocrinology Pathology [Epub ahead of print]
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PMID: 20012784
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Gramza AW, Corless CL, Heinrich MC.
Resistance to Tyrosine Kinase Inhibitors in Gastrointestinal
Stromal Tumors.
Clin Cancer Res. 2009 Dec 15;15(24):7510-7518.
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PMID: 20008851
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Troxell ML, Levine J, Beadling C, Warrick A, Dunlap J, Presnell A, Patterson J,
Shukla A, Olson NR, Heinrich MC, Corless CL.
High prevalence of PIK3CA/AKT pathway
mutations in papillary neoplasms of the breast.
Mod Pathol. 2009 Nov 6. [Epub ahead of print]
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PMID: 19898424
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Subramanian S, Thayanithy V, West RB, Lee CH, Beck AH, Zhu S, Downs-Kelly E, Montgomery K, Goldblum JR, Hogendoorn PC, Corless CL,
Oliveira AM, Dry SM, Nielsen TO, Rubin BP, Fletcher JA, Fletcher CD, van de Rijn M.
Genome-wide transcriptome analyses reveal p53
inactivation mediated loss of miR-34a expression
in malignant peripheral nerve sheath tumours.
J Pathol. 2009 Oct 1. [Epub ahead of print]
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PMID: 19890883
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Demetri GD, Heinrich MC, Fletcher JA, Fletcher CD, Van den Abbeele AD, Corless CL, Antonescu CR, George S, Morgan JA, Chen MH, Bello CL, Huang X, Cohen DP, Baum CM, Maki RG.
Molecular Target Modulation, Imaging, and Clinical Evaluation of
Gastrointestinal Stromal Tumor Patients Treated with
Sunitinib Malate after Imatinib Failure.
Clin Cancer Res. 2009 Sep 15;15(18):5902-9. Epub 2009 Sep 8.
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PMID: 19737946
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Schittenhelm MM, Kampa KM, Yee KW, Heinrich MC.
The FLT3 inhibitor tandutinib (formerly MLN518) has
sequence-independent synergistic effects with cytarabine and
daunorubicin.
Cell Cycle. 2009 Aug 15;8(16):2621-30. Epub 2009 Aug 24.
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PMID: 19625780
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Rink L, Skorobogatko Y, Kossenkov AV, Belinsky MG, Pajak T, Heinrich MC, Blanke CD, von Mehren M, Ochs MF, Eisenberg B, Godwin AK.
Gene expression signatures and response to imatinib mesylate
in gastrointestinal stromal tumor.
Mol Cancer Ther. 2009 Aug;8(8):2172-82. Epub 2009 Aug 11.
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PMID: 19671739
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Janeway KA, Albritton KH, Van Den Abbeele AD, D'Amato GZ, Pedrazzoli P, Siena S, Picus J, Butrynski JE, Schlemmer M, Heinrich MC, Demetri GD.
Sunitinib Treatment in Pediatric Patients With Advanced GIST
Following Failure of Imatinib.
Pediatr Blood Cancer. 2009 Jul;52(7):751-2.
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PMID: 19326424
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Pantaleo MA, Astolfi A, Di Battista M, Heinrich MC, Paterini P, Scotlandi K, Santini D, Catena F, Manara MC, Nannini M, Maleddu A, Saponara M, Lolli C, Formica S, Biasco G.
Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential
novel therapeutic target.
Int J Cancer. 2009 May 28. [Epub ahead of print].
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PMID: 19672856
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Tyner JW, Deininger MW, Loriaux MM, Chang BH, Gotlib JR, Willis SG, Erickson H, Kovacsovics T, O'Hare T, Heinrich MC, Druker BJ.
RNAi screen for rapid therapeutic target identification in leukemia patients.
Proc Natl Acad Sci U S A. 2009 May 26;106(21):8695-700. Epub 2009 May 11.
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PMID: 19433805
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Ustun C, Corless CL, Savage N, Fiskus W, Manaloor E, Heinrich MC, Lewis G, Ramalingam P, Kepten I, Jillella A, Bhalla K.
Chemotherapy and dasatinib induce long-term hematologic and molecular
remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V.
Leuk Res. 2009 May;33(5):735-41.
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PMID: 18986703
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Jennifer Dunlap, Claudia Le, Arielle Shukla, Janice Patterson, Ajia Presnell, Michael C. Heinrich, Christopher L. Corless, and Megan L. Troxell.
Phosphatidylinositol-3-Kinase and AKT1 Mutations Occur Early in Breast Carcinoma.
Breast Cancer Res Treat. 2009 May 6. Epub ahead of print.
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Liegl B, Hornick JL, Corless CL, Fletcher CD.
Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes.
Am J Surg Pathol. 2009 Mar;33(3):437-46.
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PMID: 19011564
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Schittenhelm MM, Kollmannsberger C, Oechsle K, Harlow A, Morich J, Honecker F, Kurek R, Störkel S, Kanz L, Corless CL, Wong KK, Bokemeyer C, Heinrich MC.
Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.
Mol Cancer Ther. 2009 Mar;8(3):481-9. Epub 2009 Mar 10.
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PMID: 19276157
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Tyner JW, Erickson H, Deininger MW, Willis SG, Eide CA, Levine RL, Heinrich MC, Gattermann N, Gilliland DG, Druker BJ, Loriaux MM.
High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients.
Blood. 2009 Feb 19;113(8):1749-55. Epub 2008 Dec 15.
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PMID: 19075190
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Liegl B, Hornick JL, Antonescu CR, Corless CL, Fletcher CD.
Rhabdomyosarcomatous differentiation in gastrointestinal
stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression.
Am J Surg Pathol. 2009 Feb;33(2):218-26.
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PMID: 18830121
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Eisenberg BL, Harris J, Blanke CD, Demetri GD, Heinrich MC, Watson JC, Hoffman JP, Okuno S, Kane JM, von Mehren M.
Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent
operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665.
J Surg Oncol. 2009 Jan 1;99(1):42-7.
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PMID: 18942073
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Hess CJ, Feller N, Denkers F, Kelder A, Merle PA, Heinrich MC, Harlow A, Berkhof J, Ossenkoppele GJ, Waisfisz Q, Schuurhuis GJ.
Correlation of minimal residual disease cell frequency with molecular genotype in patients with acute myeloid leukemia.
Haematologica. 2009 Jan;94(1):46-53. Epub 2008 Nov 27.
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PMID: 19042917